What You Get Predictive Risk Indices

17 Predictive Risk Indices

17 clinical risk scores - the same formulas your doctor uses, computed automatically from your blood.

A normal lab report only tells you whether a single value is in or out of range. Predictive indices look across multiple markers to calculate your actual disease risk - years before symptoms appear.

Your report computes 17 of these indices automatically, including HOMA-IR, FIB-4, and Framingham CVD risk. No extra tests needed.

17
Validated clinical indices - computed automatically from your standard blood test parameters. No additional tests needed.

All 17 Indices

1
HOMA-IR
Insulin resistance - (glucose × insulin) / 22.5
Matthews et al., 1985
Metabolic
2
FIB-4
Liver fibrosis staging - (Age × AST) / (Platelets × √ALT)
Sterling et al., 2006
Liver
3
FLI (Fatty Liver Index)
Hepatic steatosis probability - logistic regression on TG, BMI, GGT, waist
Bedogni et al., 2006
Liver
4
VAI (Visceral Adiposity Index)
Visceral fat dysfunction - gender-specific formula with waist, TG, HDL, BMI
Amato et al., 2010
Metabolic
5
Framingham/COX Risk
10-year cardiovascular disease risk - gender-specific Cox regression
D'Agostino et al., 2008
Heart
6
TyG Index
Triglyceride-glucose surrogate for insulin resistance - ln(TG × FPG) / 2
Simental-Mendía et al., 2008
Metabolic
7
AIP (Atherogenic Index of Plasma)
Atherogenic risk - log10(TG / HDL) in mmol/L
Dobiasova, 2004
Heart
8
APRI
AST-to-platelet ratio for fibrosis - (AST/ULN) / Platelets × 100
Wai et al., 2003
Liver
9
Remnant Cholesterol
Residual CVD risk beyond LDL - TC − LDL − HDL
Nordestgaard et al., 2014
Heart
10
Non-HDL Cholesterol
ACC/AHA primary lipid target - TC − HDL
ACC/AHA Guidelines
Heart
11
TC/HDL Ratio
Castelli Risk Index I - total cholesterol / HDL cholesterol
Castelli et al.
Heart
12
LDL/HDL Ratio
Castelli Risk Index II - LDL cholesterol / HDL cholesterol
Castelli et al.
Heart
13
NLR (Neutrophil-to-Lymphocyte Ratio)
Systemic inflammation and immune stress marker
Forget et al., 2017
Inflammation
14
NFS (NAFLD Fibrosis Score)
Advanced fibrosis in fatty liver - age, BMI, AST/ALT, platelets, albumin
Angulo et al., 2007
Liver
15
De Ritis Ratio
Liver injury pattern - AST / ALT (differentiates alcoholic vs. non-alcoholic)
De Ritis et al., 1957
Liver
16
PLR (Platelet-to-Lymphocyte Ratio)
Inflammatory response and thrombotic risk marker
Templeton et al., 2014
Inflammation
17
T3/T4 Ratio
Thyroid conversion efficiency - Free T3 / Free T4
Hoermann et al., 2015
Thyroid

How Each Index Is Presented

Every index in your report includes:

Frequently Asked Questions

What are predictive clinical risk indices in a blood test report?

Predictive clinical risk indices are validated formulas derived from blood biomarkers that quantify your risk for specific conditions. For example, HOMA-IR predicts insulin resistance, FIB-4 predicts liver fibrosis risk, and the Framingham Cardiovascular Score estimates your 10-year heart disease probability — all computed from your standard blood test without any extra panels.

What is HOMA-IR and what does it mean?

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) is calculated as (Fasting Insulin × Fasting Glucose) / 405. A value above 2.5 indicates insulin resistance, which is a precursor to Type 2 diabetes even when fasting glucose appears normal. It is one of the most clinically useful indices for detecting early metabolic disease before it shows up in standard tests.

How many risk indices does Smart Health Report calculate?

Smart Health Report computes 17 validated clinical indices: HOMA-IR, FIB-4 (liver fibrosis), Framingham CVD Score, TyG Index (insulin resistance), AIP (atherogenic index of plasma), NLR (neutrophil-to-lymphocyte ratio), eGFR (kidney function), Uric Acid Risk Index, and 9 more — all derived from your standard blood test data, each with peer-reviewed citations.

Get Your 17 Predictive Indices

All 17 indices computed from a standard blood test. No extra panels needed.

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