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17 Predictive Risk Indices

Published, peer-reviewed clinical formulas that predict disease risk years before symptoms appear. Each index includes thresholds, interpretation, and the original research citation.

17
Validated clinical indices — computed automatically from your standard blood test parameters. No additional tests needed.

All 17 Indices

1
HOMA-IR
Insulin resistance — (glucose × insulin) / 22.5
Matthews et al., 1985
Metabolic
2
FIB-4
Liver fibrosis staging — (Age × AST) / (Platelets × √ALT)
Sterling et al., 2006
Liver
3
FLI (Fatty Liver Index)
Hepatic steatosis probability — logistic regression on TG, BMI, GGT, waist
Bedogni et al., 2006
Liver
4
VAI (Visceral Adiposity Index)
Visceral fat dysfunction — gender-specific formula with waist, TG, HDL, BMI
Amato et al., 2010
Metabolic
5
Framingham/COX Risk
10-year cardiovascular disease risk — gender-specific Cox regression
D'Agostino et al., 2008
Heart
6
TyG Index
Triglyceride-glucose surrogate for insulin resistance — ln(TG × FPG) / 2
Simental-Mendía et al., 2008
Metabolic
7
AIP (Atherogenic Index of Plasma)
Atherogenic risk — log10(TG / HDL) in mmol/L
Dobiasova, 2004
Heart
8
APRI
AST-to-platelet ratio for fibrosis — (AST/ULN) / Platelets × 100
Wai et al., 2003
Liver
9
Remnant Cholesterol
Residual CVD risk beyond LDL — TC − LDL − HDL
Nordestgaard et al., 2014
Heart
10
Non-HDL Cholesterol
ACC/AHA primary lipid target — TC − HDL
ACC/AHA Guidelines
Heart
11
TC/HDL Ratio
Castelli Risk Index I — total cholesterol / HDL cholesterol
Castelli et al.
Heart
12
LDL/HDL Ratio
Castelli Risk Index II — LDL cholesterol / HDL cholesterol
Castelli et al.
Heart
13
NLR (Neutrophil-to-Lymphocyte Ratio)
Systemic inflammation and immune stress marker
Forget et al., 2017
Inflammation
14
NFS (NAFLD Fibrosis Score)
Advanced fibrosis in fatty liver — age, BMI, AST/ALT, platelets, albumin
Angulo et al., 2007
Liver
15
De Ritis Ratio
Liver injury pattern — AST / ALT (differentiates alcoholic vs. non-alcoholic)
De Ritis et al., 1957
Liver
16
PLR (Platelet-to-Lymphocyte Ratio)
Inflammatory response and thrombotic risk marker
Templeton et al., 2014
Inflammation
17
T3/T4 Ratio
Thyroid conversion efficiency — Free T3 / Free T4
Hoermann et al., 2015
Thyroid

How Each Index Is Presented

Every index in your report includes:

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All 17 indices computed from a standard blood test. No extra panels needed.

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